Perinatal High-Salt Diet Induces Gut Microbiota Dysbiosis, Bile Acid Homeostasis Disbalance, and NAFLD in Weanling Mice Offspring

Perinatal High-Salt Diet Induces Gut Microbiota Dysbiosis, Bile Acid Homeostasis Disbalance, and NAFLD in Weanling Mice Offspring

A perinatal high-salt (HS) diet was reported to elevate plasma triglycerides. This study aimed to investigate the hypothesis that a perinatal HS diet predisposed offspring to non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of abnormal lipid metabolism, and the possible mechanism...

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Bibliographic Details
Main Authors: Qing Guo, Yi Tang, Ying Li, Ziyuan Xu, Di Zhang, Jiangtao Liu, Xin Wang, Wei Xia, Shunqing Xu
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nutrients
Subjects:
high-salt diet
non-alcoholic fatty liver disease
hepatic inflammation
bile acid
gut microbiota
Online Access:https://www.mdpi.com/2072-6643/13/7/2135

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https://www.mdpi.com/2072-6643/13/7/2135

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