Addressing the statistical analysis dilemma that exists when analyzing clinical trial results with full efficacy using the Kaplan Meier survival analysis method

The use of a Kaplan–Meier (K–M) survival time approach is generally considered appropriate to report antimalarial efficacy trials. However, when a treatment arm has 100% efficacy, confidence intervals may not be computed. Furthermore, methods that use probability rules to handle missing data for ins...

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Bibliographic Details
Main Authors: Pimnara Peerawaranun, Rob W. van der Pluijm, Mavuto Mukaka, Brian Williamson
Format: Article
Language:English
Published: Cambridge University Press 2021-01-01
Series:Experimental Results
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2516712X21000216/type/journal_article