YabXnization platform: A monoclonal antibody heterologization server based on rational design and artificial intelligence-assisted computation

The application of antibody therapeutics is promising in the field of immunotherapy. While, heterologization should be done in most cases before applying the therapeutic antibodies into bodies, e.g., humanization, caninization and felinization for human beings, canine and feline, respectively. Here...

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Bibliographic Details
Main Authors: Xiaohu Hao, Dongping Liu, Long Fan
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024002721