Human Sirtuin Regulators: The “Success” Stories

The human sirtuins are a group of NAD+-dependent protein deacylases. They “erase” acyl modifications from lysine residues in various cellular targets including histones, transcription factors, and metabolic enzymes. Through these far-reaching activities, sirtuins regulate a diverse array of biologic...

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Bibliographic Details
Main Authors: Alyson M. Curry, Dawanna S. White, Dickson Donu, Yana Cen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.752117/full