Response of Neutrophils to Extracellular Haemoglobin and LTA in Human Blood System

Background: Haemolytic infection lyses red blood cells, releasing haemoglobin (Hb) into the plasma. Although recent studies showed that immune cells recognize redox-active cytotoxic extracellular Hb (metHb) bound to pathogen-associated molecular patterns (PAMPs), currently available information is l...

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Bibliographic Details
Main Authors: Sae-Kyung Lee, Suh Yee Goh, Yuan Qi Wong, Jeak Ling Ding
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415000043