Everything in Moderation: Lessons Learned by Exploiting Moderate Replication Stress in Cancer

The poor selectivity of standard cytotoxic chemotherapy regimens causes severe side-effects in patients and reduces the quality of life during treatment. Targeting cancer-specific vulnerabilities can improve response rates, increase overall survival and limit toxic side effects in patients. Oncogene...

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Bibliographic Details
Main Authors: Deborah Nazareth, Mathew J. K. Jones, Brian Gabrielli
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/9/1320