Comparison of PCR and Viable Count as a Method for Enumeration of Bacteria in an A/J Mouse Aerosol Model of Q Fever

Comparison of PCR and Viable Count as a Method for Enumeration of Bacteria in an A/J Mouse Aerosol Model of Q Fever

Historically, disease progression in animal models of Q fever has been carried out using PCR to monitor the presence of Coxiella burnetii DNA in the host. However, the colonization and dissemination of other bacterial infections in animal models are tracked using viable counts, enabling an accurate...

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Bibliographic Details
Main Authors: M. Gill Hartley, Esther Ralph, Isobel H. Norville, Joann L. Prior, Timothy P. Atkins
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
Coxiella
viability
mouse model
PCR
counts
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01552/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01552/full

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