Sex-Dependent Changes in Right Ventricular Gene Expression in Response to Pressure Overload in a Rat Model of Pulmonary Trunk Banding

Right ventricular hypertrophy (RVH) and subsequent failure are consequences of pulmonary arterial hypertension (PAH). While females are four times more likely to develop PAH, male patients have poorer survival even with treatment, suggesting a sex-dependent dimorphism in right ventricular (RV) hyper...

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Bibliographic Details
Main Authors: Hicham Labazi, Julie Birkmose Axelsen, Dianne Hillyard, Margaret Nilsen, Asger Andersen, Margaret R. MacLean
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/8/10/430