Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke

Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke

Background Translocation of lipopolysaccharide from gram‐negative bacteria into the systemic circulation results in endotoxemia. In addition to acute infections, endotoxemia is detected in cardiometabolic disorders, such as cardiovascular diseases and obesity. Methods and Results We performed a geno...

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Bibliographic Details
Main Authors: Jaakko Leskelä, Iiro Toppila, Mari‐Anne Härma, Teemu Palviainen, Aino Salminen, Niina Sandholm, Milla Pietiäinen, Elisa Kopra, Jean‐Paul Pais de Barros, Mariann I. Lassenius, Anmol Kumar, Valma Harjutsalo, Kajsa Roslund, Carol Forsblom, Anu Loukola, Aki S. Havulinna, Laurent Lagrost, Veikko Salomaa, Per‐Henrik Groop, Markus Perola, Jaakko Kaprio, Markku Lehto, Pirkko J. Pussinen
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
coagulation
contact activation
endotoxin
gene
genome‐wide association study
lipopolysaccharide
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.022482

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.121.022482

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