Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency Reversal

Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency Reversal

Persistence of latently infected cells in presence of Anti-Retroviral Therapy presents the main obstacle to HIV-1 eradication. Much effort is thus placed on identification of compounds capable of HIV-1 latency reversal in order to render infected cells susceptible to viral cytopathic effects and imm...

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Bibliographic Details
Main Authors: Mateusz Stoszko, Elisa De Crignis, Casper Rokx, Mir Mubashir Khalid, Cynthia Lungu, Robert-Jan Palstra, Tsung Wai Kan, Charles Boucher, Annelies Verbon, Emily C. Dykhuizen, Tokameh Mahmoudi
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:EBioMedicine
Subjects:
HIV
Latency
BAF complex
Chromatin remodeling
latency reversal agents
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415302309

Internet

http://www.sciencedirect.com/science/article/pii/S2352396415302309

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