Dissecting pathophysiology of a human dominantly inherited disease, familial amyloidotic polyneuropathy, by using genetically engineered mice
Familial amyloidotic polyneuropathy (FAP) is a type of systemic amyloidosis characterized by peripheral and autonomic neuropathy. Although FAP is a typical autosomal dominant disorder caused by a point mutation in the TTR gene, the average age at onset varies significantly among different countries....
| मुख्य लेखकों: | , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
De Gruyter
2022-05-01
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| श्रृंखला: | Frigid Zone Medicine |
| ऑनलाइन पहुंच: | https://doi.org/10.2478/fzm-2022-0009 |