Methods of determining optimal cut-point of diagnostic biomarkers with application of clinical data in ROC analysis: an update review
Abstract Introduction An important application of ROC analysis is the determination of the optimal cut-point for biomarkers in diagnostic studies. This comprehensive review provides a framework of cut-point election for biomarkers in diagnostic medicine. Methods Several methods were proposed for the...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-024-02198-2 |