Methods of determining optimal cut-point of diagnostic biomarkers with application of clinical data in ROC analysis: an update review

Abstract Introduction An important application of ROC analysis is the determination of the optimal cut-point for biomarkers in diagnostic studies. This comprehensive review provides a framework of cut-point election for biomarkers in diagnostic medicine. Methods Several methods were proposed for the...

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Bibliographic Details
Main Authors: Mojtaba Hassanzad, Karimollah Hajian-Tilaki
Format: Article
Language:English
Published: BMC 2024-04-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-024-02198-2