Distinct Nuclear Organization of Telomeres and Centromeres in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma

Distinct Nuclear Organization of Telomeres and Centromeres in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma

Both multiple myeloma (MM) and its precursor state of monoclonal gammopathy of undetermined significance (MGUS) are characterized by an infiltration of plasma cells into the bone marrow, but the mechanisms underlying the disease progression remain poorly understood. Previous research has indicated t...

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Bibliographic Details
Main Authors: Pak Lok Ivan Yu, Rachel R. Wang, Grace Johnston, Yaqiong Wang, Pille Tammur, Anu Tamm, Mari Punab, Aline Rangel-Pozzo, Sabine Mai
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
multiple myeloma
monoclonal gammopathy of undetermined significance
telomeres
centromeres
structural genome markers
genomic instability
Online Access:https://www.mdpi.com/2073-4409/8/7/723

Internet

https://www.mdpi.com/2073-4409/8/7/723

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