Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice

Abstract Atherogenesis is an insipidus but precipitating process leading to serious consequences of many cardiovascular diseases (CVD). Numerous genetic loci contributing to atherosclerosis have been identified in human genome-wide association studies, but these studies have limitations in the abili...

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Bibliographic Details
Main Authors: Myungsuk Kim, M. Nazmul Huda, Levi W. Evans, Excel Que, Erik R. Gertz, Nobuyo Maeda-Smithies, Brian J. Bennett
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35917-8