Discovery of Bispecific Lead Compounds from <i>Azadirachta indica</i> against ZIKA NS2B-NS3 Protease and NS5 RNA Dependent RNA Polymerase Using Molecular Simulations

Discovery of Bispecific Lead Compounds from <i>Azadirachta indica</i> against ZIKA NS2B-NS3 Protease and NS5 RNA Dependent RNA Polymerase Using Molecular Simulations

Zika virus (ZIKV) has been characterized as one of many potential pathogens and placed under future epidemic outbreaks by the WHO. However, a lack of potential therapeutics can result in an uncontrolled pandemic as with other human pandemic viruses. Therefore, prioritized effective therapeutics deve...

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Bibliographic Details
Main Authors: Sanjay Kumar, Sherif A. El-Kafrawy, Shiv Bharadwaj, S. S. Maitra, Thamir A. Alandijany, Arwa A. Faizo, Aiah M. Khateb, Vivek Dhar Dwivedi, Esam I. Azhar
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
Zika virus
NS2B-NS3 protease
NS5 RdRp
therapeutics
molecular dynamics
flavonoids
Online Access:https://www.mdpi.com/1420-3049/27/8/2562

Internet

https://www.mdpi.com/1420-3049/27/8/2562

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