Diurnal retinal and choroidal gene expression patterns support a role for circadian biology in myopia pathogenesis

Abstract The prevalence of myopia (nearsightedness) is increasing to alarming levels, but its etiology remains poorly understood. Because both laboratory and clinical findings suggest an etiologic role for circadian rhythms in myopia development, we assayed gene expression by RNA-Seq in retina and c...

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Bibliographic Details
Main Authors: Richard A. Stone, John W. Tobias, Wenjie Wei, Jonathan Schug, Xia Wang, Lixin Zhang, P. Michael Iuvone, Debora L. Nickla
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50684-2