Helicobacter pylori Vacuolating Toxin and Gastric Cancer

Helicobacter pylori VacA is a channel-forming toxin unrelated to other known bacterial toxins. Most H. pylori strains contain a vacA gene, but there is marked variation among strains in VacA toxin activity. This variation is attributable to strain-specific variations in VacA amino acid sequences, as...

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Bibliographic Details
Main Authors: Mark S. McClain, Amber C. Beckett, Timothy L. Cover
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/9/10/316