Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor

Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor

Over the last 30 years, the prevalence of osteoarthritis (OA), a disease characterized by a loss of articular cartilage, has more than doubled worldwide. Patients suffer from pain and progressive loss of joint function. Cartilage is an avascular tissue mostly consisting of extracellular matrix with...

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Bibliographic Details
Main Authors: Paul Steinwerth, Jessica Bertrand, Viviann Sandt, Shannon Marchal, Jayashree Sahana, Miriam Bollmann, Herbert Schulz, Sascha Kopp, Daniela Grimm, Markus Wehland
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomolecules
Subjects:
cartilage
tissue engineering
rotating wall vessel
simulated microgravity
scaffold-free
extracellular matrix
Online Access:https://www.mdpi.com/2218-273X/14/1/25

Internet

https://www.mdpi.com/2218-273X/14/1/25

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