Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling

Effects of sustained i.c.v. infusion of lupus CSF and autoantibodies on behavioral phenotype and neuronal calcium signaling

Abstract Systemic lupus erythematosus (SLE) is a potentially fatal autoimmune disease that is often accompanied by brain atrophy and diverse neuropsychiatric manifestations of unknown origin. More recently, it was observed that cerebrospinal fluid (CSF) from patients and lupus-prone mice can be neur...

Full description

Bibliographic Details
Main Authors: Minesh Kapadia, Dunja Bijelić, Hui Zhao, Donglai Ma, Ljudmila Stojanovich, Milena Milošević, Pavle Andjus, Boris Šakić
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Acta Neuropathologica Communications
Subjects:
CNS SLE
Autoimmunity
Cerebrospinal fluid
Brain-reactive autoantibodies
Anti-NMDA receptor
Anti-ribosomal P
Online Access:http://link.springer.com/article/10.1186/s40478-017-0473-1

Internet

http://link.springer.com/article/10.1186/s40478-017-0473-1

Similar Items