In silico design of a Zika virus non-structural protein 5 aiming vaccine protection against zika and dengue in different human populations

Abstract Background The arboviruses Zika virus (ZIKV) and Dengue virus (DENV) have important epidemiological impact in Brazil and other tropical regions of the world. Recently, it was shown that previous humoral immunity to DENV enhances ZIKV replication in vitro, which may lead to more severe forms...

Full description

Bibliographic Details
Main Authors: Lorrany dos Santos Franco, Paloma Oliveira Vidal, Jaime Henrique Amorim
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-017-0395-z