Early Depletion of Primordial Germ Cells in Zebrafish Promotes Testis Formation

Summary: As complete absence of germ cells leads to sterile males in zebrafish, we explored the relationship between primordial germ cell (PGC) number and sexual development. Our results revealed dimorphic proliferation of PGCs in the early zebrafish larvae, marking the beginning of sexual different...

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Bibliographic Details
Main Authors: Keh-Weei Tzung, Rie Goto, Jolly M. Saju, Rajini Sreenivasan, Taiju Saito, Katsutoshi Arai, Etsuro Yamaha, Mohammad Sorowar Hossain, Meredith E.K. Calvert, László Orbán
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114003336