The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.

The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.

Viroporins are small transmembrane proteins with ion channel activities modulating properties of intracellular membranes that have diverse proviral functions. Hepatitis C virus (HCV) encodes a viroporin, p7, acting during assembly, envelopment and secretion of viral particles (VP). HCV p7 is release...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Solène Denolly, Chloé Mialon, Thomas Bourlet, Fouzia Amirache, François Penin, Brett Lindenbach, Bertrand Boson, François-Loïc Cosset
Format: Artykuł
Język:English
Wydane: Public Library of Science (PLoS) 2017-12-01
Seria:PLoS Pathogens
Dostęp online:http://europepmc.org/articles/PMC5749900?pdf=render

Internet

http://europepmc.org/articles/PMC5749900?pdf=render

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