PGC-1α Is a Master Regulator of Mitochondrial Lifecycle and ROS Stress Response

Mitochondria play a major role in ROS production and defense during their life cycle. The transcriptional activator PGC-1α is a key player in the homeostasis of energy metabolism and is therefore closely linked to mitochondrial function. PGC-1α responds to environmental and intracellular conditions...

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Bibliographic Details
Main Authors: Othman Abu Shelbayeh, Tasnim Arroum, Silke Morris, Karin B. Busch
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/5/1075