68Ga-labeled WVP peptide as a novel PET probe for molecular biological diagnosis of unstable thoracic aortic aneurysm and early dissection: an animal study

68Ga-labeled WVP peptide as a novel PET probe for molecular biological diagnosis of unstable thoracic aortic aneurysm and early dissection: an animal study

ObjectiveType IV collagen (Col-IV) is a prospective biomarker for diagnosing and treating of unstable thoracic aortic aneurysm and dissection (TAAD). This study aims to evaluate the feasibility of 68Ga-labeled WVP peptide (68Ga-DOTA-WVP) as a novel Col-IV-targeted probe for TAAD biological diagnosis...

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Bibliographic Details
Main Authors: Xia Lu, Meilin Zhu, Lingzhou Zhao, Feiran Qi, Heng Zou, Peng He, Haizhong Zhou, Kuangyu Shi, Jie Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
molecular biological diagnosis
type IV collagen detection
WVP peptide
PET/CT imaging
thoracic aortic aneurysm and dissection
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1048927/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1048927/full

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