Fucoxanthin Ameliorates Sepsis via Modulating Microbiota by Targeting IRF3 Activation

Fucoxanthin Ameliorates Sepsis via Modulating Microbiota by Targeting IRF3 Activation

To improve patient survival in sepsis, it is necessary to curtail exaggerated inflammatory responses. Fucoxanthin (FX), a carotenoid derived from brown algae, efficiently suppresses pro-inflammatory cytokine expression via IRF3 activation, thereby reducing mortality in a mouse model of sepsis. Howev...

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Bibliographic Details
Main Authors: Jingqian Su, Biyun Guan, Qiaofen Su, Shan Hu, Shun Wu, Zhiyong Tong, Fen Zhou
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
sepsis
aloe emodin
inflammation
cecal ligation puncture
gut microbiota
Online Access:https://www.mdpi.com/1422-0067/24/18/13803

Internet

https://www.mdpi.com/1422-0067/24/18/13803

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