Aging, Protein Aggregation, Chaperones, and Neurodegenerative Disorders: Mechanisms of Coupling and Therapeutic Opportunities

Late onset is a key unifying feature of human neurodegenerative maladies such as Alzheimer’s and Parkinson’s diseases and prion disorders. While sporadic cases typically emerge during the patient’s seventh decade of life or later, mutation-linked, familial cases manifest during the fifth or sixth de...

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Bibliographic Details
Main Author: Ehud Cohen
Format: Article
Language:English
Published: Rambam Health Care Campus 2012-10-01
Series:Rambam Maimonides Medical Journal
Subjects:
Online Access:http://rmmj.org.il/Pages/ArticleHTM.aspx?manuId=226