The bright side of fibroblasts: molecular signature and regenerative cues in major organs

Abstract Fibrosis is a pathologic process characterized by the replacement of parenchymal tissue by large amounts of extracellular matrix, which may lead to organ dysfunction and even death. Fibroblasts are classically associated to fibrosis and tissue repair, and seldom to regeneration. However, ac...

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Bibliographic Details
Main Authors: Rita N. Gomes, Filipa Manuel, Diana S. Nascimento
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00153-z