Understanding the role of mechanics in nucleocytoplasmic transport

Cell nuclei are submitted to mechanical forces, which in turn affect nuclear and cell functions. Recent evidence shows that a crucial mechanically regulated nuclear function is nucleocytoplasmic transport, mediated by nuclear pore complexes (NPCs). Mechanical regulation occurs at two levels: first,...

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Bibliographic Details
Main Authors: Ion Andreu, Ignasi Granero-Moya, Sergi Garcia-Manyes, Pere Roca-Cusachs
Format: Article
Language:English
Published: AIP Publishing LLC 2022-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0076034