A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice

A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice

Activated M2-polarized macrophages are drivers of pulmonary fibrosis in several clinical scenarios, including Idiopathic Pulmonary Fibrosis (IPF). In this study, we investigated the effects of targeting the CD206 receptor in M2-like macrophages with a novel synthetic analogue of a naturally occurrin...

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Bibliographic Details
Main Authors: Anghesom Ghebremedhin, Ahmad Bin Salam, Benjamin Adu-Addai, Steve Noonan, Richard Stratton, Md Shakir Uddin Ahmed, Chandra Khantwal, George R. Martin, Huixian Lin, Chris Andrews, Balasubramanyam Karanam, Udo Rudloff, Henry Lopez, Jesse Jaynes, Clayton Yates
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
macrophages
myofibroblasts
IPF
immunotherapy
CD206
Online Access:https://www.mdpi.com/2073-4409/12/9/1254

Internet

https://www.mdpi.com/2073-4409/12/9/1254

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