Basic Principles of RNA Interference: Nucleic Acid Types and In Vitro Intracellular Delivery Methods

Since its discovery in 1989, RNA interference (RNAi) has become a widely used tool for the in vitro downregulation of specific gene expression in molecular biological research. This basically involves a complementary RNA that binds a target sequence to affect its transcription or translation process...

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Bibliographic Details
Main Authors: Marie Isenmann, Martin James Stoddart, Rainer Schmelzeisen, Christian Gross, Elena Della Bella, René Marcel Rothweiler
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/14/7/1321