Twist3 is required for dedifferentiation during extraocular muscle regeneration in adult zebrafish.

Severely damaged adult zebrafish extraocular muscles (EOMs) regenerate through dedifferentiation of residual myocytes involving a muscle-to-mesenchyme transition. Members of the Twist family of basic helix-loop-helix transcription factors (TFs) are key regulators of the epithelial-mesenchymal transi...

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Bibliographic Details
Main Authors: Yi Zhao, Ke'ale W Louie, Christina F Tingle, Cuilee Sha, Curtis J Heisel, Shelby P Unsworth, Phillip E Kish, Alon Kahana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231963