The clinical potential of optogenetic interrogation of pathogenesis

Abstract Background Opsin‐based optogenetics has emerged as a powerful biomedical tool using light to control protein conformation. Such capacity has been initially demonstrated to control ion flow across the cell membrane, enabling precise control of action potential in excitable cells such as neur...

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Bibliographic Details
Main Authors: Tianyu Terry Gao, Teak‐Jung Oh, Kritika Mehta, Yu‐En Andrew Huang, Tyler Camp, Huaxun Fan, Jeong Won Han, Collin Michael Barnes, Kai Zhang
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/ctm2.1243