Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk

Calcified aortic valve disease (CAVD), the most common valvular heart disease, lacks pharmaceutical treatment options because its pathogenesis remains unclear. This disease with a complex macroenvironment characterizes notable cellular heterogeneity. Therefore, a comprehensive understanding of cellu...

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Bibliographic Details
Main Authors: Qian Zhou, Hong Cao, Xiaoyi Hang, Huamin Liang, Miaomiao Zhu, Yixian Fan, Jiawei Shi, Nianguo Dong, Ximiao He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CAVD
scRNA-seq
cell communication
VICs’ calcification
midkine (MDK)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.794058/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.794058/full

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