Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress

Effects of liraglutide on astrocyte polarization and neuroinflammation in db/db mice: focus on iron overload and oxidative stress

Neuroinflammation plays a crucial role in the occurrence and development of cognitive impairment in type 2 diabetes mellitus (T2DM), but the specific injury mechanism is not fully understood. Astrocyte polarization has attracted new attention and has been shown to be directly and indirectly involved...

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Bibliographic Details
Main Authors: Ji-Ren An, Jun-Tong Liu, Xiao-Meng Gao, Qing-Feng Wang, Gui-Yan Sun, Jia-Nan Su, Chi Zhang, Jia-Xiang Yu, Yu-Feng Yang, Yan Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
diabetic cognitive impairment
hippocampus
neuroinflammation
astrocyte polarization
iron overload
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1136070/full

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https://www.frontiersin.org/articles/10.3389/fncel.2023.1136070/full

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