TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma

Abstract Background Deregulated Hippo signaling has been uncovered to be intricately involved in tumorigenesis. Transcriptional factor TEADs serve as key mediators of Hippo signaling and have been increasingly appreciated as putative oncogenes driving cancer initiation and progression. However, its...

Full description

Bibliographic Details
Main Authors: Wei Zhang, Jin Li, Yaping Wu, Han Ge, Yue Song, Dongmiao Wang, Hua Yuan, Hongbing Jiang, Yanling Wang, Jie Cheng
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Cancer Cell International
Subjects:
Head and neck squamous cell carcinoma
Hippo signaling
TEAD4
EMT
Prognostic biomarker
Online Access:http://link.springer.com/article/10.1186/s12935-018-0675-z

Internet

http://link.springer.com/article/10.1186/s12935-018-0675-z

Similar Items