Host CD3+ T-cells can significantly modulate phage treatment effects on bacterial bioburden in mouse models

Host CD3+ T-cells can significantly modulate phage treatment effects on bacterial bioburden in mouse models

Wound healing is a complex system including such key players as host, microbe, and treatments. However, little is known about their dynamic interactions. Here we explored the interplay between: (1) bacterial bioburden and host immune responses, (2) bacterial bioburden and wound size, and (3) treatme...

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Bibliographic Details
Main Authors: Renhua Li, Michael Rouse, Brendon T. Pace, Scott F. Grey, Kimberly Mclaughlin, Seth A. Schobel, Mark P. Simons
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Microbiology
Subjects:
wound healing
phage treatment
bacterial bioburden
CD3+ T-cells
systems biology
bi-directional relationship between bacterial burden and host immune responses
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1240176/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1240176/full

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