Biodereplication of Antiplasmodial Extracts: Application of the Amazonian Medicinal Plant <i>Piper coruscans</i> Kunth

Biodereplication of Antiplasmodial Extracts: Application of the Amazonian Medicinal Plant <i>Piper coruscans</i> Kunth

Improved methodological tools to hasten antimalarial drug discovery remain of interest, especially when considering natural products as a source of drug candidates. We propose a biodereplication method combining the classical dereplication approach with the early detection of potential antiplasmodia...

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Bibliographic Details
Main Authors: Pedro G. Vásquez-Ocmín, Jean-François Gallard, Anne-Cécile Van Baelen, Karine Leblanc, Sandrine Cojean, Elisabeth Mouray, Philippe Grellier, Carlos A. Amasifuén Guerra, Mehdi A. Beniddir, Laurent Evanno, Bruno Figadère, Alexandre Maciuk
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
<i>Piper coruscans</i> Kunth (Piperaceae)
biodereplication
heme binding
mass spectrometry
<i>Plasmodium</i>
Online Access:https://www.mdpi.com/1420-3049/27/21/7638

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https://www.mdpi.com/1420-3049/27/21/7638

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