Design of a novel Fischer carbene complex which can facilitate thiol mediated site-specific protein immobilization
A novel Fischer carbene complex has been synthesized which has tuneable reactivity owing to its dual functionality to facilitate binding with peptides and proteins via thiol moiety in presence of the amine groups of abundant lysine residues. The Fischer carbene has been so designed that it can be ma...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-01-01
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| Series: | Results in Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715622001382 |