PDCL2 is essential for spermiogenesis and male fertility in mice

Abstract Patients with teratozoospermia exhibit low phosducin-like protein (Pdcl2) expression. As a member of the phosducin family, chaperonin-related Pdcl2, a germline-specific gene, may be involved in germ cell protein folding. Given that PDCL2 is highly conserved in evolution, it may be indispens...

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Bibliographic Details
Main Authors: Minyan Li, Yuxi Chen, Jianping Ou, Junjiu Huang, Xiya Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2022-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01210-2