Anti-CD38 Antibody Therapy: Windows of Opportunity Yielded by the Functional Characteristics of the Target Molecule

Abstract In vivo use of monoclonal antibodies (mAbs) has become a mainstay of routine clinical practice in the treatment of various human diseases. A number of molecules can serve as targets, according to the condition being treated. Now entering human clinical trials, CD38 molecule is a particularl...

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Bibliographic Details
Main Authors: Antonella Chillemi, Gianluca Zaccarello, Valeria Quarona, Manuela Ferracin, Chiara Ghimenti, Massimo Massaia, Alberto L. Horenstein, Fabio Malavasi
Format: Article
Language:English
Published: BMC 2013-04-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.2119/molmed.2013.00009