Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee

Abstract Background This study was designed to test the hypothesis that blockade of vascular endothelial growth factor (VEGF) suppresses degenerative changes in articular cartilage from patients with osteoarthritis (OA). Methods Articular cartilage from eight OA patients was subjected to explant cul...

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Bibliographic Details
Main Authors: Masaichi Sotozawa, Ken Kumagai, Kimi Ishikawa, Shunsuke Yamada, Yusuke Inoue, Yutaka Inaba
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-03512-2