Unraveling Transcriptome Profile, Epigenetic Dynamics, and Morphological Changes in Psoriasis-like Keratinocytes: “Insights into Similarity with Psoriatic Lesional Epidermis”

Unraveling Transcriptome Profile, Epigenetic Dynamics, and Morphological Changes in Psoriasis-like Keratinocytes: “Insights into Similarity with Psoriatic Lesional Epidermis”

Keratinocytes are one of the primary cells affected by psoriasis inflammation. Our study aimed to delve deeper into their morphology, transcriptome, and epigenome changes in response to psoriasis-like inflammation. We created a novel cytokine mixture to mimic mild and severe psoriasis-like inflammat...

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Bibliographic Details
Main Authors: Ameneh Ghaffarinia, Szilárd Póliska, Ferhan Ayaydin, Aniko Goblos, Shahram Parvaneh, Máté Manczinger, Fanni Balogh, Lilla Erdei, Zoltán Veréb, Kornélia Szabó, Zsuzsanna Bata-Csörgő, Lajos Kemény
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
psoriasis
keratinocyte
cytokine
inflammation
transcriptome
5-methylcytosine (5-mC)
Online Access:https://www.mdpi.com/2073-4409/12/24/2825

Internet

https://www.mdpi.com/2073-4409/12/24/2825

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