The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study

The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study

Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood.Methods: To explore the molecular profile of AD and aged platelets, we investigated platelet activation...

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Main Authors: Diana M. Bessa de Sousa, Rodolphe Poupardin, Saul A. Villeda, Adam B. Schroer, Thomas Fröhlich, Vanessa Frey, Wolfgang Staffen, Heike Mrowetz, Barbara Altendorfer, Michael S. Unger, Bernhard Iglseder, Bernhard Paulweber, Eugen Trinka, Janne Cadamuro, Martin Drerup, Katharina Schallmoser, Ludwig Aigner, Kathrin M. Kniewallner
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Alzheimer’s disease
aging
platelets
proteomics
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1196083/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1196083/full

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