A Hydrodistillate of <i>Gynostemma pentaphyllum</i> and Damulin B Prevent Cisplatin-Induced Nephrotoxicity In Vitro and In Vivo via Regulation of AMPKα1 Transcription

A Hydrodistillate of <i>Gynostemma pentaphyllum</i> and Damulin B Prevent Cisplatin-Induced Nephrotoxicity In Vitro and In Vivo via Regulation of AMPKα1 Transcription

The clinical application of cisplatin, one of the most effective chemotherapeutic agents used to treat various cancers, has been limited by the risk of adverse effects, notably nephrotoxicity. Despite intensive research for decades, there are no effective approaches for alleviating cisplatin nephrot...

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Bibliographic Details
Main Authors: Minhyeok Song, Minseok Kim, Dang Hieu Hoang, Lochana Mangesh Kovale, Jihyun Lee, Youngjoo Kim, Changhyun Lee, Jongki Hong, Sungchul Park, Wonchae Choe, Insug Kang, Sung Soo Kim, Joohun Ha
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Nutrients
Subjects:
<i>Gynostemma pentaphyllum</i>
damulin B
AMPKα1
nephrotoxicity
cisplatin
Online Access:https://www.mdpi.com/2072-6643/14/23/4997

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https://www.mdpi.com/2072-6643/14/23/4997

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