Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium

Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium

Abstract Animal models are widely used for biomedical studies and drug evaluation. The small intestine plays key roles in nutrient absorption, hormone secretion, microbiota defense and drug absorption and metabolism. Although the intestinal structure of mammals is conserved, the differences on epith...

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Bibliographic Details
Main Authors: Haonan Li, Xiaodan Wang, Yalong Wang, Mengxian Zhang, Fan Hong, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji, Ye-Guang Chen
Format: Article
Language:English
Published: SpringerOpen 2022-05-01
Series:Cell Regeneration
Subjects:
scRNA-seq
Transcriptome
Ileum
Monkey
Pig
Rat
Online Access:https://doi.org/10.1186/s13619-022-00118-7

Internet

https://doi.org/10.1186/s13619-022-00118-7

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