A high-content screen reveals new regulators of nuclear membrane stability
Abstract Nuclear membrane rupture is a physiological response to multiple in vivo processes, such as cell migration, that can cause extensive genome instability and upregulate invasive and inflammatory pathways. However, the underlying molecular mechanisms of rupture are unclear and few regulators h...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-03-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-56613-1 |