Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders

Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders

The identification of multilocus imprinting disturbances (MLID) appears fundamental to uncover molecular pathways underlying imprinting disorders (IDs) and to complete clinical diagnosis of patients. However, MLID genetic associated mechanisms remain largely unknown. To characterize MLID in Beckwith...

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Bibliographic Details
Main Authors: L. Fontana, M. F. Bedeschi, S. Maitz, A. Cereda, C. Faré, S. Motta, A. Seresini, P. D’Ursi, A. Orro, V. Pecile, M. Calvello, A. Selicorni, F. Lalatta, D. Milani, S. M. Sirchia, M. Miozzo, S. Tabano
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:Epigenetics
Subjects:
beckwith-wiedemann syndrome
silver-russell syndrome
multilocus imprinting disturbances
targeted next-generation sequencing
epigenotype-phenotype correlations
Online Access:http://dx.doi.org/10.1080/15592294.2018.1514230

Internet

http://dx.doi.org/10.1080/15592294.2018.1514230

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