Serum Markers of Blood-Brain Barrier Remodeling and Fibrosis as Predictors of Etiology and Clinicoradiologic Outcome in Intracerebral Hemorrhage

Serum Markers of Blood-Brain Barrier Remodeling and Fibrosis as Predictors of Etiology and Clinicoradiologic Outcome in Intracerebral Hemorrhage

Background: Intracerebral hemorrhage (ICH) is a stroke subtype associated with high disability and mortality. There is a clinical need for blood-based biomarkers that can aid in diagnosis, risk stratification, and prognostication. Given their role in the pathophysiology of ICH, we hypothesized marke...

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Bibliographic Details
Main Authors: Matthew D. Howe, Liang Zhu, Lauren H. Sansing, Nicole R. Gonzales, Louise D. McCullough, Nancy J. Edwards
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Neurology
Subjects:
intracerebral hemorrhage
biomarker
matrix metalloproteinase
fibronectin
TGF beta
cerebral amyloid angiopathy
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00746/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.00746/full

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