Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology – A proof-of-concept study

Summary: Background: The lack of detectable precancerous lesions poses challenges to the early detection of human papillomavirus-driven oropharyngeal cancer (HPV-OPC). Antibodies against HPV16 early proteins, especially E6, are uniquely sensitive and specific biomarkers detectable years prior to HP...

Full description

Bibliographic Details
Main Authors: Chia-Jung Busch, Anna Sophie Hoffmann, Daniele Viarisio, Benjamin T. Becker, Thorsten Rieckmann, Christian Betz, Noemi Bender, Lea Schroeder, Yassin Hussein, Elina Petersen, Annika Jagodzinski, Ines Schäfer, Eike Burandt, Krystle Lang Kuhs, Michael Pawlita, Tim Waterboer, Nicole Brenner
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:EClinicalMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537022003893