Atrial Natriuretic Peptide Acts as a Neuroprotective Agent in in Vitro Models of Parkinson’s Disease via Up-regulation of the Wnt/β-Catenin Pathway

Atrial Natriuretic Peptide Acts as a Neuroprotective Agent in in Vitro Models of Parkinson’s Disease via Up-regulation of the Wnt/β-Catenin Pathway

In the last decades increasing evidence indicated a crucial role of the Wnt/β-catenin signaling in development of midbrain dopaminergic (mDA) neurons. Recently dysregulation of this pathway has been proposed as a novel pathomechanism leading to Parkinson’s disease (PD) and some of the molecules part...

Full description

Bibliographic Details
Main Authors: Arianna Colini Baldeschi, Eugenia Pittaluga, Federica Andreola, Simona Rossi, Mauro Cozzolino, Giuseppe Nicotera, Gianluca Sferrazza, Pasquale Pierimarchi, Annalucia Serafino
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
Wnt/β-catenin pathway
neurodegeneration
atrial natriuretic peptide
neuroprotection
Parkinson’s disease
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00020/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00020/full

Similar Items